2. Respiratory System

Respiratory Tract infection	IV treatment	Oral treatment
Exacerbation of CHRONIC BRONCHITIS	Amoxicillin 500mg tds	Amoxicillin 500mg tds (1st line) Co-amoxiclav 375mg - 625mg tds (2nd line)
Uncomplicated community acquired PNEUMONIA – Unknown aetiology	Amoxicillin 500mg tds or Clarithromycin 500mg bd	Amoxicillin 250mg – 500mg tds or Cefixime 200mg bd or 400mg od
Uncomplicated community acquired PNEUMONIA – unknown aetiology if ALLERGIC to PENICILLIN	Clarithromycin 500mg bd	Erythromycin 250mg – 500mg qds  (Erymax 500mg bd at Wythenshawe)
SEVERE community acquired PNEUMONIA –unknown aetiology	Cefuroxime 1.5g tds plus Clarithromycin 500mg bd plus Flucloxacillin 2g qds (if staphylococcal infection suspected eg. post influenza)	Cefixime 200mg bd or 400mg od or Erythromycin 500mg qds  (Erymax 500mg bd at Wythenshawe)
ATYPICAL PNEUMONIA	Clarithromycin 500mg bd	Erythromycin 250mg – 500mg qds  (Erymax 500mg bd at Wythenshawe)
HOSPITAL ACQUIRED PNEUMONIA	Cefuroxime 750mg - 1.5g tds	Cefixime 200mg bd or 400mg od or Ciprofloxacin 250 - 500mg bd (use with caution in patients with a history of epilepsy or conditions predisposing them to seizures)
HOSPITAL ACQUIRED PNEUMONIA -aspiration	Cefotaxime 1 - 2g tds plus Metronidazole 500mg tds	Cefixime 200mg bd or 400mg od or Ciprofloxacin 250 - 500mg bd (use with caution in patients with a history of epilepsy or conditions predisposing them to seizures) plus Metronidazole 400mg tds