Licensed medicines and their unlicensed uses

Approved by the Trust Medicines Management Committee

Carbamazepine

nerve pain

Amitriptyline

Phenytoin

Sodium valproate

Triptafen

IBS

Motival

IBS

Spironolactone

hirsutism

Cyproterone

Ketoconazole

Finasteride

Octreotide

nausea, vomiting, haemoptysis

Allopurinol

free radical scavenger

Mycophenolate

lung transplantation, bronchiolitis obliterans, IV in cardiac transplant

Clonidine

opioid sparing

Thalidomide

multiple myeloma, oropharyngeal ulceration

Fluoxetine 40mg

depression

Tinzaparin

anticoagulant during pregnancy

Erythromycin

increasing gut motility

Olanzapine

depression

Ketamine

phantom limb pain

Megestrol

appetite stimulant

Nifedipine

hiccups, oesophageal spasm, pre-eclampsia

Adalat LA 120mg

hypertension

Ciclosporin

inflammatory bowel disease

Sodium Valproate

bipolar mood disorder

Phenytoin

Lamotrigine

Olanzapine

Quetiapine

Pramipexol

Clopidogrel

post PTCA & stent

Tacrolimus

heart transplant

Cyclophosphamide

heart & lung transplantation

Streptokinase

pleural effusion

Erymax

Pseudomonas in CF

Clarithromycin

Clonazepam

restless legs

Epoprostenol

primary pulmonary hypertension

Gastrografin

meconium ileus

Inosine pranobex

alopecia

Misoprostol

induction of labour in TOP (oral/vaginally), post-partum haemorrhage

Nifedipine

myometrial relaxant for inhibition of uncomplicated premature labour

Azithromycin

Pseudomonas aeruginosa in CF patients

Ursodeoxycholic acid

preservation of liver function in CF patients with abnormal LFTs or scans

Leukotriene receptor antagonists (montelukast, zafirlukast)

reduction of spasm elasticity

Rituximab

resistant rejection & autoimmune haemolytic anaemia in transplant patients, cryoglobulinaemia

Infliximab

wegener's granulomatosis

Sirolimus

lung fibrosis

Botulinum toxin (Dysport/Botox)

Achalasia, spasmodic dysphonia

Amended June 2005