4.8 Antiepileptics

4.8.1 Control of epilepsy

 

Carbamazepine liquid 100mg/5ml

F

See Therapeutic Drug Monitoring

Carbamazepine tabs 100mg, 200mg, 400mg

F

Carbamazepine SR tabs 200mg, 400mg

F

Clonazepam tablets 500mcg, 2mg

F

 

Ethosuxamide capsules 250mg

R

Paediatrics

Ethosuxamide syrup 250mg/5ml

R

Paediatrics

Gabapentin capsules 100mg, 300mg, 400mg

F

For neuropathic pain. See Palliative Care Guidelines

Lamotrigine tablets 25mg, 50mg,100mg

R

Neurology

Lamotrigine disp tabs 5mg, 25mg

R

Neurology

Levetiracetam tabs

R

Neurology

Oxcarbazepine tabs

R

Neurology

Phenobarbital elixir 15mg/5ml

F

See Therapeutic Drug Monitoring

CD

Phenobarbital injection 15mg/1ml 30mg/1ml, 200mg/1ml

F

Phenobarbital tablets 15mg, 30mg, 60mg, 100mg

F

Phenytoin sodium caps 25mg, 50mg, 100mg

F

See Therapeutic Drug Monitoring

 
Chronic pain consultants only
Use BD dosing where possible

Phenytoin suspension 30mg/5ml

F

Phenytoin chewable tablets 100mg

F

Pregabalin capsules 25mg, 50mg, 75mg, 100mg, 150mg, 200mg

R

Primidone suspension 250mg/5ml

F

Sodium valproate injection 400mg/4ml

F

See Therapeutic Drug Monitoring

 

Sodium valproate liquid 200mg/5ml

F

Sodium valproate chewable tabs 100mg

F

Sodium valproate EC tabs 200mg, 500mg

F

Sodium valproate MR tabs 20mg, 300mg, 500mg (Epilim Chrono)

F

Tiagabine tabs

R

Neurology

Topiramate tabs 50mg, 100mg, 200mg

R

Neurology

Vigabatrin tablets 500mg

R

Paediatrics

Vigabatrin powder 500mg

R

Neurology

 

4.8.1 Drugs used in status epilepticus

 

 

Clonazepam injection 1mg/1ml

F

 

Diazepam injection (emulsion) 10mg/2ml

F

 

Diazepam rectal solution 5mg, 10mg

F

 

Lorazepam injection 4mg/ml

F

 

Paraldehyde Injection

R

Paraldehyde no longer has a licence and must be requested on a named patient basis

Phenytoin injection 250mg/5ml

F

 

N.B. Lorazepam should be given initially in preference to Diazepam due to its longer duration of action and lower risk of thrombophlebitis. Diazepam should not be administered intramuscularly for treatment of status epilepticus as absorption is slow and erratic.