4.2 Drugs used in psychoses and related disorders

4.2 Drugs used in psychoses and related disorders *
Chlopromazine injection 25mg/1ml, 50mg/2ml	F
Chlorpromazine liquid 25mg/5ml, 100mg/5ml	F
Chlorpromazine suppositories 100mg	F
Chlorpromazine tablets 10mg, 25mg, 50mg, 100mg	F
Haloperidol capsules 500mcg	F
Haloperidol injection 5mg/1ml, 20mg/2ml	F
Haloperidol liquid 2mg/1ml, 10mg/5ml	F
Levomepromazine injection 25mg/1ml	R	Palliative Care
Levomepromazine mixture 25mg/5ml	R	Palliative Care
Levomepromazine tablets 25mg	R	Palliative Care
Promazine liquid 50mg/5ml	F
Promazine tablets 25mg, 50mg	F
Quetiapine tablets 25mg, 100mg, 150mg, 200mg, 300mg	F	See notes below
Risperidone tablets 500mcg, 1mg, 2mg, 3mg, 4mg, 6mg	F	See notes below
Risperidone liquid 1mg/ml	F

Risperidone/Olanzapine

In March 2004 the CSM recommended that risperidone and olanzapine should not be used for the behavioural symptoms of dementia or for the treatment of psychosis where there is a history of stroke/TIA or risk factors for cerebrovascular events. This is due to an increased risk of stroke and TIAs (for every 6 patients with dementia treated, one extra cerebrovascular event could be expected to occur). It is possible that this risk extends to all atypical antipsychotics but current recommendations do not contra-indicate use of quetapine, however all atypicals should be avoided.

For patients admitted on these agents, guidance is available at

www.rcgp.org.uk/corporate/position/drugs.asp

* See NICE guidance for Schizophrenia - atypical antipsychotics

4.2.2 Antipsychotic depot injections
Contact Pharmacy Department if necessary for details of items stocked.